Report of a Case of Sclerema Neonatorum
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Sclerema Neonatorum Treated Successfully with Parenteral Steroids: An Experience from a Resource Poor Country
Sclerema neonatorum is a form of panniculitides characterized by diffuse hardening of subcutaneous tissue with minimal inflammation. It usually affects ill and preterm neonates. Prognosis is usually poor in many cases despite aggressive management. Various treatment modalities (antibiotics, intravenous immunoglobulin, steroids, and exchange transfusion) have been explained in literature. Steroi...
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The fatty crystals in three previously published cases of sclerema neonatorum were identified by means of x-ray diffraction as sodium stearate and palmitic acid. A composite view of the pathogenesis of both sclerema neonatorum and adiponecrosis cutis neonatorum is discussed.
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Sclerema neonatorum (SN) is a rare disease characterized by firm, indurated, waxy skin lesions extending throughout the body, sparing the fat-free soles, palms, and genitalia. The prognosis of SN is generally very poor, with a high fatality rate. We report the case of a full-term infant with delayed onset of SN showing good prognosis. A 4-month-old Korean male infant presented with diffuse waxy...
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Sclerema neonatorum is a rare disease of earlv infancy, characterized by swellings in the subcutaneous fat, of characteristic distribultion on the back, shoulders, buttocks, and cheeks. In these lesions the fat crystallizes out during life, probably as reutral fat, and in well-marked cases the crystals give rise to an inflammatory reaction of the " foreign body " type, with giant cells. In thes...
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Many writers use the terms ' sclerema neonatorum ' and ' adiponecrosis subcutanea neonatorum' in a synonymous sense, and this has caused some confusion, although the real and clinically useful distinction drawn by Gray (1926) between the generalized and serious variety of subcutaneous fat necrosis, and the localized and benign type has become widely accepted. In this paper two cases of the loca...
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